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Allplex™
HPV HR Detection

Throughout the world, more than 600,000 woman are being diagnosed annually with cervical cancer that is caused by human papillomavirus (HPV)¹⁾. However, the risk of cervical cancer can be predicted and prevented if high-risk HPV types are detected in early stages with regular screening.

WHO recommends DNA testing for primary cervical cancer screening¹⁾ and the recent trends show that screening method is shifting from the cytology test to HPV DNA test. Furthermore, the prevalence of HPV type is different across the world due to increasing vaccination and difference in regional characteristics²⁾, leading DNA testing more useful in screening HPVs.

Allplex™ HPV HR Detection is a multiplex real-time PCR assay that enables simultaneous amplification and detection of target nucleic acids of 14 high-risk HPV types (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68) as well as Internal Control (IC).

Key feature
  • Short PCR turn-around time (TAT)

    1.5 hours of PCR TAT
  • Fully automated workflow

    Application of Seegene STARlet-AIOS™ providing
    one streamlined workflow from nucleic acids extraction to result analysis
  • Self-collected samples

    Increased accessibility of HPV screening
    due to alternative sample collection method, enabling early prevention of cervical cancer
  • 14 high-risk HPV genotypes

    Detecting and identifying 14 individual HPVs simultaneously with a single test
    Monitoring of clearance and persistence
    of HPV genotypes and the risk of cervical cancer
  • Individual Ct values

    Seegene 3 Ct PCR technology provides Ct values to infer viral load, helping clinicians to provide personalized patient care with more precise diagnosis

Specification

Analytes Specimens Compatible instrumentation

Analytes

14 high-risk HPV types
(16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68)

Internal control (IC)

Specimens

Cervical specimen

Self-collected vaginal specimen

Compatible instrumentation

Automated extraction
& PCR setup
Seegene STARlet
Seegene STARlet-AIOS™
Seegene STARlet 96MPH
Seegene NIMBUS

Automated extraction
SEEPREP32™

Real-time PCR
CFX96™ Dx
CFX96™

Ordering information

Product Volume Cat. No.

Product

Allplex™ HPV HR Detection

Volume

25 rxns
100 rxns
100 rxns x 8 Kits

Cat. No.

HP10371Z
HP10370X
HP10376L

Product

Volume

25 rxns
100 rxns

Cat. No.

HP10373Z
HP10372X

Product

Volume

100 rxns

Cat. No.

HP7E00X

Product

Volume

100 rxns

Cat. No.

HP7S00X

1) WHO guideline for screening and treatment of cervical cancer prevention. 2nd ed. Geneva: World Health Organization; 2021.
2) Latsuzbaia A et al. Effectiveness of bivalent and quadrivalent human papillomavirus vaccination in Luxembourg. Cancer Epidemiol. 2019 Dec;63:101593.