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Novaplex™
MPXV/OPXV plus Assay
Mpox, caused by the monkeypox virus(MPXV), a species in the genus Orthopoxvirus (OPXV), leads to symptoms such as painful rashes, fever, mucosal lesions, and lymphadenopathy. While most cases recover, it can be fatal for certain populations. A global outbreak occurred in 2022 due to Clade II. In 2024, Clade I, which has higher transmissibility and mortality, is spreading rapidly, prompting the WHO to declare a Public Health Emergency of International Concern (PHEIC) in August 2024.

Novaplex™ MPXV/OPXV plus Assay (RUO) detects the MPXV, as well as OPXV, the genus to which MPXV belongs, while providing additional information to distinguish and detect Clade I.
Key features

  • Capable of distinguishing and detecting
    MPXV Clade (I)

    Provides reliable test results with broad coverage for all subtypes of MPXV clades I and II, with specific confirmation of Clade I, known for its higher mortality rate

  • Simultaneous testing solution

    Co-testing with the Novaplex™ Genital ulcer Assay enables differentiation or co-detection of agents in samples with similar symptoms

  • Dual internal controls ensuring highly reliable result

    Uses dual internal controls (Endo IC and Exo IC) to verify the validity of the sample and the pre-analytical process

Specifications

Analytes Compatible instrumentation

•Monkeypox Virus (MPXV I/II)

•Monkeypox Virus Clade I (MPXV I)

•Non-variola Orthopoxvirus (OPXV)

•Endogenous internal control (Endo IC)

•Exogenous internal control (Exo IC)

•Automated extraction & PCR Setup
Seegene NIMBUS
Seegene STARlet

•Real-time PCR
CFX96™ Real-time PCR Detection System
CFX96™ Dx System
CFX96 Touch™ Real-Time PCR Detection System

Ordering information

Product Volume Cat. No

Novaplex™ MPXV/OPXV plus Assay (RUO)

100 rxns

25 rxns

R-PX70607X

R-PX70608Z
*For research use only. Not for use in diagnostic procedures.