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  • Real-time
  • CE-IVD

Anyplex™ II
MTB/MDR/XDR Detection

Simultaneous detection of MTB, 25 mutations associated with Multi-Drug Resistance tuberculosis (MDR-TB) and 13 mutations associated with Extensively Drug Resistance tuberculosis (XDR-TB)

Anyplex™ II MTB/MDR/XDR Detection is a multiplex real-time PCR assay that detect Mycobacterium tuberculosis (MTB) with Ct value and identify 38 mutations associated with Drug-Resistance simultaneously. Based on Seegene’s proprietary DPO™ and TOCE™ technologies, this assay performs on multiplex real-time PCR instruments and provide prompt diagnosis and appropriate treatment guideline for tuberculosis control.

Key Features and Benefits

  • Multiplex real-time PCR

    Simultaneous detection of Mycobacterium tuberculosis and 25 mutations associated with MDR-TB

  • Wild-type Control

    WTC[1](Wild-type Control) and Internal Control (IC) for assay validity

  • DNA extraction solution

    Reagent for DNA Detection is provided, purchase of DNA extraction kit is unnecessary

  • Wide range of specimens

    Wide range of applicable specimens

  • Fast treatment decision

    Fast treatment decision by simultaneous screening and subtyping

  • Whole process validation

    Whole process validation from extraction to PCR by whole process control

  • Automatic data analyzer

    Automated data interpretation and LIS interlocking with Seegene Viewer

  • Automatic data analyzer

    Automated data interpretation and LIS interlocking with Seegene Viewer

  • Prediction of antibiotic resistance

    Detection and identification of mutations associated antibiotic resistance for appropriate infection control

  • Analytes

    • Mycobacterium tuberculosis (MTB)
    • Internal Control (IC)
  • Multi-Drug Resistance (MDR)
    • Isoniazid-resistance (7 mutations) [2]
    • Rifampicin-resistance (18 mutations) [2]
    • Internal Control (IC)
  • Extensively Drug Resistance (XDR)
    • Fluoroquinolone-resistance (7 mutations) [3]
    • Injectable drug-resistance (6 mutations) [3]
    • Internal Control (IC)
  • Specimens

    • Sputum
    • Bronchial washing
    • Cultured cell
    • Fresh tissue
  • Ordering Information

    Cat No. / Size
    Anyplex™ II MTB/MDR/XDR Detection
    TB7500Y / 50 rxns


The results indicate the detection of MTB infection in the FAM channel, and the rifampicin-resistance mutation in the HEX channel and the Isoniazid-resistance mutation in the Cal Red 610 channel.


[1] The WTC is designed to be exhibited the same result pattern with drug-susceptible M. tuberculosis sample. The WTC reaction should be always performed in each testing run, and the drug-resistant result of unknown samples is analyzed on the basis of the result of WTC.

[2] Multi-Drug Resistance

[3] Extensively Drug Resistance