Magicplex™ Sepsis Real-time Test

Detection of Sepsis-causing Pathogens

  • Real time
  • CE IVD
NOT AVAILABLE IN THE US

Outline

Magicplex™ Sepsis Real-time Test screens for more than 90 pathogens which cover over 90%1),2),3) of sepsis-causing pathogens from whole blood samples within 3 hrs (exclude extraction time).

Sepsis, systemic inflammatory response syndrome, is known as top 10 disease with high mortality in the United States. Specially, it may lead to fatal consequences such as shock, organ failure, death to ICU patients, children, elderly, and post-surgery patients with weak immune system. Early diagnosis and treatment are important for fast-paced sepsis progress. Treatment should not be delayed as statistics suggest that as high as an 8% of mortality rate increases per hour if antibiotics are delayed in severe sepsis cases.

However, Magicplex™ Sepsis Real-time Test screens pathogens as well as tests for methicillin and vancomycin resistance within 3 hrs (after extraction). Also, this test is able to further identify the pathogens which are detected in the previous screening step with an additional 30 min.

1) Biedenbach et al. (2004) Diagn Microbiol Infect Dis 50(1):59-69
2) Wisplinghoff et al. (2004) Clin Infect Dis 39(3) :309-317
3) Koh et al. (2007) Korean J Lab Med 27(4):265-275.

Features

  1. High sensitivity
  2. Direct test from whole blood
  3. Screening for more than 90 pathogens (>90% of sepsis causative pathogens) as well as 3 drug-resistant markers within 3 hrs after extraction
  4. Further identification of 27 pathogens detected within 30 min with no additional amplification.

Analytes

Amplification Screening
Amplicon Bank 1. Gram (+) bacteria / DR Gram (+) bacteria Screening
73 Gram (+) bacteria
3 Drug resistance markers
Streptococcus spp.
Enterococcus spp.
Staphylococcus spp.
  Drug Resistance (DR) Screening
  vanA        vanB        mecA
Amplicon Bank 2. Gram (-) bacteria / Fungi Gram (-) bacteria / Fungi Screening
12 Gram(-)bacreria
6 fungi
Gram (-) bacteria-A
Gram (-) bacteria-B
Fungi

Identification  
ID 1 . Streptococcus spp. ID 2 . Enterococcus spp.
S. agalactiae
S. pyogenes
S. pneumoniae
E. faecalis
E. gallinarum
E. faecium
ID 3 . Staphylococcus spp.  
S. epidermidis
S. haemolyticus
S. aureus
 
ID 4 . Gram (-) bacteria-A ID 5 . Gram (-) bacteria-A
P. aeruginosa
A. baumannii
S. maltophilia
S. marcescens
B. fragilis
S. typhi
ID 6 . Gram (-) bacteria- B ID 7 . Gram (-) bacteria- B
K. pneumoniae
K. oxytoca
P. mirabilis
E. coli
E. cloacae
E. aerogenes
ID 8 . Fungi ID 9 . Fungi
C. albicans
C. tropicalis
C. parapsilosis
C. glabrata
C. krusei
A. fumigatus

Specimen

- Whole Blood  

Result Preview

CFX96™ Real-time PCR System



option
  Gram (+) bacteria Screening Drug Resistance Screening Enterococcus ID
(ID 2)
FAM Whole Process Control Whole Process Control Whole Process Control
HEX Streptococcus spp. vanA E. faecalis
CAL Red 610 Enterococcus spp. vanB E. gallinarum
Quasar 670 Staphylococcus spp. mecA E. faecium
(CFX96™ Real-time PCR System)

Ordering Information

Product Cat. No. Size
Sepsis Amplification SE8000Y 50 rxns
Sepsis Screening Real-time Detection * SE8T01Y 50 rxns
Sepsis ID 1~9 Real-time Detection * SE8301Y~SE8309Y 50 rxns
*In case of SmartCycler® II System, total rxn number is 40 rxns. (50 rxns → 40 rxns)

If you are interested in finding more about this product,
please do not hesitate to contact us

Real-time : Real-time PCR
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