Seeplex®VRE ACE Detection

Detection of vanA & vanB genes which cause vancomycin-resistance

  • ACE
NOT AVAILABLE IN THE US

Outline

Enterococci are normally indigenous bacteria found in the GI tract and female genitals, but recently they are recognized as major pathogens causing urinary tract infections and sepsis by nosocomial infection.

Vancomycin, which is used in the treatment of enterococci infection, is a drug that has an antibacterial effect by forming a complex with the D-alanyl-D-alanine terminal of the peptidoglycan precursor to block transglycosylation and transpeptidation during the synthesis of the cell wall of Gram-positive cocci. However, vancomycin-resistant enterococci (VRE) tends to multiply rapidly due to the high frequency and continuous use of vancomycin.

The Seeplex® VRE ACE Detection is a PCR method that incorporates DPO™ technology with high sensitivity and specificity, and is a product that can test for the vancomycin- resistant vanA gene and the vanB gene of enterococci in one test.

Features

  1. Single PCR test identify vanA and vanB genes causing of Vancomycin-resistant of enterococci
  2. Multiplex PCR with high sensitivity and specificity by applying DPO™ (Dual Priming Oligonucleotide) technology
  3. Applicable for Auto-capillary Electrophoresis device
  4. A single round PCR process reduces the carryover contamination risk, and 8-MOP, which is included in product, eliminates the contamination risk from PCR products
  5. Accurate system for result interpretation included Internal Control and Positive Control

Analytes

- vanA - vanB

Specimens

- Cultured Enterococosel Broth/Agar

Compatible Instruments

Result Preview

ID Result
1 vanA
2 vanB
3 -*
4 -*
5 vanA
6 vanA
1~6: Stool samples cultured in enterococcosel broth
* Not detected


Ordering Information

Product Cat. No. Size
Seeplex® VRE ACE Detection VR1210Y 50 rxns

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ACE : Automatic capillary electrophoresis
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