Allplex™Meningitis Panel Assays

Essential screening assay for the detection and identification of
18 meningitis pathogens using multiplex one-step Real-time RT-PCR

  • REAL TIME
  • CE IVD
NOT AVAILABLE IN THE US

Outline

Viral and bacterial infections are the most common causes of meningitis. Since the viral and bacterial meningitis exhibit similar signs and symptoms, it is difficult to diagnose meningitis. Moreover, it is challenging to differentiate partially pre-treated bacterial meningitis with viral meningitis with current diagnostic methods. Therefore, there are many unnecessary antibiotic treatments given to patients and prolonged duration of hospital admissions.

Culture and stain of cerebrospinal fluid (CSF) are typical diagnostic methods used for meningitis. However, due to limited sensitivity of those methods, it is challenging to obtain accurate results in CSF collected from patients with pre-treatment of antibiotics. The use of real-time PCR with relatively enhanced sensitivity for detection of meningitis pathogens overcomes those challenges.

Allplex™ Meningitis Panel Assays is a multiplex one-step Real-time RT-PCR assay that detects and identifies 18 meningitis causative pathogens including 12 viruses, 6 bacteria. Based on Seegene’s proprietary MuDT technology, it allows reporting of multiple Ct values of each pathogen in a single channel without melt curve analysis.

Features

  1. Simultaneous detection and identification of 12 viruses and 6 bacteria causing meningitis
  2. Multiplex One-step Real-time RT- PCR assay within 2 hours after extraction
  3. Individual Ct values for multiple targets in a single reaction
  4. Flexible choices of target-based panels for effective patient care
  5. Automatic data interpretation by Seegene Viewer

Analytes

Panel 1 Panel 2 Panel 3
Virus (I) Virus (II) Bacteria
- Herpes simplex virus type 1
- Herpes simplex virus type 2
- Varicella-zoster virus
- Epstein-barr virus
- Cytomegalovirus
- Human herpesvirus 6
- Human herpesvirus 7
- Parvovirus B19
- Mumps virus
- Parechovirus
- Adenovirus
- Enterovirus
- Haemophilus influenzae
- Streptococcus pneumoniae
- Listeria monocytogenes
- Neisseria meningitidis
- Group B Streptococcus
- E.coli K1

Specimen

- Cerebrospinal fluid (CSF)

Result Preview


The result represents co-infection of EBV, VZV and HSV2 in Cal Red 610 and HEX channels with Ct values of 39.35 (Graph 1) and 24.54 (Graph 2), 31.04 (Graph 2), respectively.

Ordering Information

Product Cat. No. Size
Allplex™ Meningitis-V1 Assay MG9700Y
MG9700X
50 rxns
100 rxns*
Allplex™ Meningitis-V2 Assay MG9500Y
MG9500X
50 rxns
100 rxns*
Allplex™ Meningitis-B Assay MG9600Y
MG9600X
50 rxns
100 rxns*
*For use with Microlab NIMBUS IVD & STARlet IVD only.

If you are interested in finding more about this product,
please do not hesitate to contact us

Real-time : Real-time PCR
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