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Drug Resistance Detection
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Detection of vanA & vanB genes
which cause vancomycin-resistance |
Seeplex® VRE ACE Detection is designed to detect the
vanA and vanB genes which cause vancomycin
-resistance in enterococci isolated from stool
culture in a single test.
(Analyzing product, DNA amplification )
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NOT AVAILABLE IN THE US
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Enterococci are
normally indigenous bacteria found in the GI tract and female
genitals, but recently they were recognized as major pathogens
causing urinary tract infections and sepsis by nosocomial
infection.
Vancomycin, which is used in the treatment of enterococci infection, is a drug that has
an antibacterial effect by forming a complex with the D-alanyl-D-alanine terminal of the
peptidoglycan precursor to block transglycosylation and transpeptidation during the
synthesis of the cell wall of Gram-positive cocci. However, vancomycin-resistant
enterococci (VRE) tend to multiply rapidly due to the high frequency and continuous
use of vancomycin.
The Seeplex® VRE ACE Detection is a PCR method that incorporates DPO™ technology
with high sensitivity and specificity, and is a product that can test for the vancomycin-
resistant vanA gene and the vanB gene of enterococci in one test. |
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| A. |
Single PCR test identifying vanA, vanB gene cause of Vancomycin-resistant of enterococci. |
| B. |
Applicable for Auto-capillary Electrophoresis device |
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Test result is rapidly and easily obtained by automating band reading and analysis process after PCR. |
| C. |
Contamination Prevention System |
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One-time PCR reduces the carryover contamination risk, and 8-MOP, which is included in each set of products, eliminates the contamination risk from PCR. |
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| D. |
Multiplex PCR with high sensitivity and specificity by applying DPO™ (Dual Priming Oligonucleotide) technology |
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DPO- based primers contain two priming parts, so that the target gene only is specifically amplified. |
| E. |
Accurate system for interpretation of results |
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Internal Control and Positive Control are included in each set of products.
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| - Enterococci cultured
in Enterococcosel
broth /agar |
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- vanA
- vanB
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ScreenTape®
System
(Agilent
Technologies)
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MCE®-202
MultiNA
SHIMADZU
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| Product |
Cat. No. |
Size |
| Seeplex® VRE ACE Detection |
VR1201Y |
50 rxns |
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- As this product is Medical Device, please read 'caution' and 'instruction' before use.
- Deliberation number : 2013-I10-01-0833
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