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Infectious Pathogen Detection
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Detection of viruses and
bacteria causing human meningitis |
Seeplex® Meningitis ACE Detection
detects viruses
and/or bacteria causing
human meningitis
from cerebrospinal fluid
(CSF).
(Analyzing product, DNA amplification )
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NOT AVAILABLE IN THE US
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Bacterial meningitis has an incidence of about 20 to 100 cases per 100,000 live births during the newborn period. Aseptic meningitis is even more common. Although most types of aseptic meningitis do not cause serious symptoms, some types result in significant morbidity and mortality if not properly diagnosed and treated.
Early identification of causative bacterial and viral pathogens is important for prompt and proper treatment of meningitis and for prevention of life-threatening clinical outcomes.
In meningitis, identification of pathogen as well as early detection is critical for efficient treatment. Current diagnostic methods for meningitis such as CSF culture and Latex agglutination assay have certain limitations such as time factor and low sensitivity. With multiplex PCR system based on DPO™ technology, the Seeplex® Meningitis ACE Detection can detect 7 viruses (6 types of DNA virus (HSV1, 2, CMV, EBV, VZV, HHV6) and RNA virus (HEV)) and 5 bacteria (Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, Group B Streptococcus, Listeria monocytogenes) causing meningitis within 6 hours.
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| A. |
Differentiates 7 meningitis causative viruses and 5 kinds of bacteria with a single PCR. |
| B. |
Multiplex PCR with high sensitivity and specificity by applying DPO™ (Dual Priming Oligonucleotide) technology |
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DPO™ primer has two different priming portions which allows to specifically amplifies target DNAs. |
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Applicable for Auto-detection instruments |
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In addition to Agarose gel electrophoresis, application of Auto-detection system provides easy and convenient results read-out. |
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Accurate system for interpretation of results |
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Internal Control and Positive Control are included in product. |
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Contamination Prevention System |
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One-time PCR reduces the carryover contamination risk, and 8-MOP, which is included in product, eliminates the contamination risk from PCR. |
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| Virus 1 panel |
HSV 1
HSV 2
VZV (HHV3)
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EBV (HHV4)
CMV (HHV5) (CE0086)
HHV6 |
| Virus 2 panel |
Enteroviruses*
*Enteroviruses primer designed to detect Poliovirus, Echovirus, and Coxsachievirus. |
| Bacteria panel |
Streptococcus pneumoniae
Neisseria meningitidis
Haemophilus influenzae
Listeria monocytogenes
Group B Streptococcus (Streptococcus agalactiae) |
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| - Cerebrospinal fluid (CSF) |
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Caliper
LabChip® Dx
(CALIPER
LIFESCIENCES)
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MCE®-202
MultiNA
SHIMADZU
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ScreenTape®
System
(Agilent
Technologies)
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| Products |
Cat. No. |
Size |
Seeplex® Meningitis-V1 ACE Detection (V2.0)
Seeplex® Meningitis-V2 ACE Detection (V2.0)
Seeplex® Meningitis-B ACE Detection (V2.0) |
MG6611Y
MG6111Y
MG6501Y
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50 rxns
50 rxns
50 rxns |
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| *Note: Seeplex® Meningitis Products are available for each individual sale. |
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- As this product is Medical Device, please read 'caution' and 'instruction' before use.
- Deliberation number : 2013-I10-01-0831
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