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SNP Detection
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| Detection of the MTHFR C677T and A1298C |
Seeplex® MTHFR C677T/A1298C ACE is
designed to detect the MTHFR C677T
and A1298C simultaneously from blood samples.
(Analyzing product, DNA amplification )
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NOT AVAILABLE IN THE US |
MTHFR is a key enzyme in folic acid metabolism, which catalyzes the synthesis of methionine through re-methylation of homocysteine to methionine1).
Seeplex® MTHFR C677T/A1298C ACE by adopting DPO™ technology is a unique product PCR testing MTHHFR C677T and A1298C without additional steps such as sequencing, restriction enzyme digestion.
1) Jae-Hong Park, et. al., Journal of the Korean Rheumatism Association, Vol. 10, No. 3, 283-292, 2003. |
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| A. |
Identification of mutations of MTHFR (C677T & A1298C) with single PCR reaction |
| B. |
Multiplex PCR with high sensitivity and specificity by applying DPO™ (Dual Priming Oligonucleotide) technology |
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DPO™ based primers contain two priming parts so that only target gene is specifically amplified. |
| C. |
Applicable for Auto-capillary Electrophoresis detection device |
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Rapid and easy interpretation of the result can obtained by applying Agarose gel electrophoresis, as well as auto-detection system. |
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| D. |
Contamination Prevention System |
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One-time PCR reduces the carryover contamination risk, and 8-MOP, which is included in product, eliminates the contamination risk from PCR. |
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Accurate system for interpretation of results |
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Internal Control and Positive Control are included in product. |
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- MTHFR 677C
- MTHFR 677T
- MTHFR 1298A
- MTHFR 1298C |
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- Whole blood |
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Caliper
LabChip® Dx
(CALIPER
LIFESCIENCES)
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MCE®-202
MultiNA
SHIMADZU
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ScreenTape®
System
(Agilent
Technologies)
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| Product |
Cat. No. |
Size |
| Seeplex® MTHFR C677T/A1298C ACE |
MT1210Z |
25 rxns |
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- As this product is Medical Device, please read 'caution' and 'instruction' before use.
- Deliberation number : 2013-I10-01-0825
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