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Infectious Pathogen Detection
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Detection of M. tuberculosis (MTB)
in various specimens |
Seeplex® MTB Nested ACE Detection
is
designed to
detect Mycobacterium
tuberculosis (MTB) from
paraffin tissue and biopsy specimens.
(Analyzing product, DNA amplification )
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NOT AVAILABLE IN THE US
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Seeplex® MTB Nested ACE Detection is designed to detect Mycobacterium tuberculosis (MTB), IS6110 and MPB64, using nested PCR. IS6110 is an insertion sequence present in the MTB genome. As most MTB have one to twenty copies of it, its presence is a useful indicator in tuberculosis tests. There have, however, been reports1) of MTB strains without this gene, and in such a case, the accuracy of diagnosis can be enhanced by testing simultaneously for IS6110 and MPB64,2) which is a conserved sequence present in single copy in the MTB genome.
As simultaneously amplifying IS6110 and MPB64 genes based on the nested PCR, Seeplex® MTB Nested ACE Detection can effectively eliminate false negative results and be a useful method for detection of MTB.
1) Juana Magdalena, et. al., J. Clin. Microbiol. 1998; 36(4); 937-943.
2) Naoki Hasegawa, et. al., J. Clin. Micobiol. 2002; 40(3); 908-912.
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| A. |
Internal Control is included (acquisition of tests reliability) |
| B. |
Detection of MTB from paraffin tissue |
| C. |
Optimize sensitivity by Nested PCR |
| D. |
Simultaneous amplification of IS6110 MPB64 DNAs |
| E. |
DNA Extraction Solution is provided |
| F. |
viewer software is provided for convenient read-out. |
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- MTB
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| - Tissue (fresh tissue, paraffin-embedded tissue) |
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- Sputum
- Bronchial washing |
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Caliper
LabChip® Dx
(CALIPER
LIFESCIENCES)
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MCE®-202
MultiNA
SHIMADZU
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ScreenTape®
System
(Agilent
Technologies)
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| Product |
Cat. No. |
Size |
| Seeplex® MTB Nested ACE Detection |
TB2110Y |
50 rxns |
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- As this product is Medical Device, please read 'caution' and 'instruction' before use.
- Deliberation number : 2013-I10-01-0819
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