Simultaneously screening for STD and HPV high-risk/low-risk
The Seeplex® HPV/STD4 ACE Screening for auto-capillary electrophoresis system is designed to simultaneously screen for the most common STD and HPV high-risk/low-risk types from patients’ samples (cervical/urethral swabs). The Seeplex® HPV/STD4 ACE Screening detects the most common STD-causing pathogens, Chlamydia trachomatis and Neisseria gonorrhoeae and detects 13 high-risk HPVs and 5 low-risk HPVs, separately. It is a very useful diagnostic method for prevention and timely treatment of STD and cervical cancer because two most frequently detected STD-causing pathogens and high-risk HPV causing cervical cancer can be separately detected in a single tube.	(CE1023 for CT)
Introducing a useful reference for diagnosis of HPVs: Castle P.E. et al. The potential utility of HPV Genotyping in screening and clinical management. 2008. J Natl Compr Canc Netw 6(1):83-95. (review) Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) are the main cause of bacterial infections transmitted by sexual contact. Each year 25 million people and 50 million people suffer from gonorrhoeae and chlamydia, respectively. Gonorrhoeae and chlamydia have hard times diagnosing due to the following reasons. First, both diseases share the common symptoms and a complication. Secondly, infected women are mostly asymptomatic. Finally, when women are co-infected with both NG and CT, the symptoms overlap from both infections. However, without any treatments, the diseases can cause infertility in women, and Pelvic Inflammatory Disease (PID) leading to extrauterine pregnancy. In addition, an infant from infected mother has a higher chance of acquiring conjunctivitis and pneumonia. Therefore, accurate and rapid early diagnosis is absolutely critical. High-risk Human Papillomavirus (HPV) is known to be the main cause of cervical cancer; hence, HPV diagnostic tests are being developed to detect the wide variety of HPVs. Currently, Pap test is widely being used to screen women for cervical cancer caused by HPVs; however, there is a high rate of false- negatives due to low sensitivity and specificity. Fig. & Table. Example Figure & Table. Amplified PCR products using Seeplex® HPV/STD4 ACE Screening. (Rapid & easy interpretation using ScreenTape® System) Features - Simultaneous screening for STD and HPV high-risk/low-risk types - Multiplex PCR with high sensitivity and specificity by applying DPO™ (Dual Priming Oligonucleotide) technology DPO™ (NET* approved) based primers contain two priming parts so that only target gene is specifically amplified. *NET (New Excellent Technology) is approved Korea Ministry of Education, Science, and Technology. -  Applicable for Auto-capillary Electrophoresis device PCR amplicons are separated and analyzed automatically; consequently, rapid and easy interpretation of the results is made possible. - Contamination Prevention System One-time PCR reduces the carryover contamination risk, and 8-MOP, which is included in each set of products, eliminates the contamination risk from PCR. -  Accurate system for interpretation of results Internal control and positive control are included in each set of products. Order information   Product Cat. No. Size   Seeplex® HPVSTD4 ACE Screening SH1400Y 50 rxns * Note: If you need more information for the primer mixture, please contact us.

* Storage:
Short term storage : 4℃
Long term storage : -20℃
In case of the 2X Multiplex Master Mix, 4 ℃ for short-term storage and -20℃ for long-term
storage are recommended. Avoid repetitive thawing/freezing as it may decrease the activity
of the Master Mix.


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