Simultaneously genotyping (HPVs 16 and 18) and screening
The Seeplex® HPV4 ACE Screening is designed to simultaneously genotype (HPVs 16 and 18) and screen for HPV 11 high-risk and 5 low-risk types from patients’ samples (cervical swabs). Cervical cancer, which progresses from the precancerous stage to invasive cancer, has 7-20 years of precancerous stage; consequently early diagnosis is possible when HPV infection is suspected. HPV low-risk group, including HPVs 6 and 11, may cause genital warts. On the other hand, HPV high-risk group may lead to the development of cervical cancer; especially, HPVs 16 and 18 are associated with 70% of cervical cancer case. Seeplex® HPV4 ACE Screening can indentify HPVs 16 and 18 and also screen for HPV high and low-risks at the same time.
Introducing a useful reference for diagnosis of HPVs: Castle P.E. et al. The potential utility of HPV Genotyping in screening and clinical management. 2008. J Natl Compr Canc Netw 6(1):83-95. (review) Fig. & Table. Example   Click the image for large view. Figure & Table. Amplified PCR products using Seeplex® HPV4 ACE Screening (Rapid & easy interpretation using ScreenTape® System) Features - Simultaneous genotyping ( HPV 16, 18) and screening for HPV high-risk and low-risk types - Multiplex PCR with high sensitivity and specificity by applying DPO™ (Dual Priming Oligonucleotide) technology DPO ™ (NET* approved) based primers contain two priming parts so that only target gene is specifically amplified. *NET (New Excellent Technology) is approved Korea Ministry of Education, Science, and Technology. -  Applicable for Auto-capillary Electrophoresis device PCR amplicons are separated and analyzed automatically; consequently, rapid and easy interpretation of the results is made possible. - Contamination Prevention System One-time PCR reduces the carryover contamination risk, and 8-MOP, which is included in each set of products, eliminates the contamination risk from PCR. -  Accurate system for interpretation of results Internal control and positive control are included in each set of products. Order information   Product Cat. No. Size   Seeplex® HPV4 ACE Screening (CE mark)   HP1400Y 50 rxns * Note: If you need more information for the primer mixture, please contact us.

* Storage:
Short term storage : 4℃
Long term storage : -20℃
In case of the 2X Multiplex Master Mix, 4 ℃ for short-term storage and -20℃ for long-term
storage are recommended. Avoid repetitive thawing/freezing as it may decrease the activity
of the Master Mix.


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