Seegene Inc

Not Available for sale in the United States

  • Real-time
  • CE-IVD

Anyplex™ II
HPV28 Detection

Simultaneous detection and identification of 28 HPV types (19 high-risk and 9 low-risk)

Anyplex™Ⅱ HPV28 Detection simultaneously detects, differentiates and quantifies 28 distinct HPV genotypes (19 high-risk and 9 low-risk) responsible for cervical cancer and/or sexually transmitted infections. Based on Seegene’s proprietary DPO™ and TOCE™ technologies, this multiplex assay performs on  real-time PCR instrument and provides high sensitivity and specificity genotyping information of infected 28 HPV types in a single reaction



The result represents co-infection that HPV 16 is high (+++) in the HEX channel, HPV 52 is high(+++) in the Cal Red 610 channel, HPV 35, 61 are high (+++) in the Quasar 670 channel and HPV 40 is intermediate (++) in the Quasar 705 channel .


- Monitoring human papillomavirus prevalence among young Australian women undergoing routine chlamydia screening

- Human papillomavirus prevalence and distribution in self-collected samples from female university students in Maputo

- A Retrospective Study about the Impact of Switching from Nested PCR to Multiplex Real-Time PCR on the Distribution of Human papillomavirus (HPV) Genotypes 

- High Prevalence of Anal and Oral High-Risk Human Papillomavirus in Human Immunodeficiency Virus–Uninfected French Men Who Have Sex With Men and Use Preexposure Prophylaxis

- Histomorphologic assessment and distribution of high-risk human papillomavirus (HPV) types in cervical high-grade squamous intraepithelial lesions with unusual histomorphologic features

- High prevalence of cervical high-risk human papillomavirus infection mostly covered by Gardasil-9 prophylactic vaccine in adult women living in N’Djamena, Chad

- Anal human papillomavirus infections in young unvaccinated men who have sex with men attending a sexual health clinic for HPV vaccination in Melbourne, Australia

- Mutational landscape and intra‑host diversity of human papillomavirus type 16 long control region and E6 variants in cervical samples

- Prevalence of human papillomavirus, human immunodeficiency virus and other sexually transmitted infections among female sex workers in Togo: a national cross-sectional survey

- Evaluation of the Anyplex II HPV28 Assay in the Detection of Human Papillomavirus in Archival Samples of Oropharyngeal Carcinomas

- Effectiveness of bivalent and quadrivalent human papillomavirus vaccination in Luxembourg

- Prognostic value of pre-treatment human papilloma virus DNA status in cervical cancer

- Unusual and unique distribution of anal high-risk human papillomavirus (HR-HPV) among men who have sex with men living in the Central African Republic

- A Review and Update on Papillary Immature Metaplasia of the Uterine Cervix

- High-grade anal intraepithelial neoplasia (AIN) is associated with HIV-1 RNA rectal shedding in virologically suppressed MSM

- Findings of multiple HPV genotypes in cervical carcinoma are associated with poor cancer-specific survival in a Swedish cohort of cervical cancer primarily treated with radiotherapy

- Prevalence of Sexually Transmitted Infections among Married Women in Rural Nepal

- Continuing global improvement in human papillomavirus DNA genotyping services: The 2013 and 2014 HPV LabNet international proficiency studies

- Safety and acceptability of human papillomavirus testing of self-collected specimens: A methodologic study of the impact of collection devices and HPV assays on sensitivity for cervical cancer and high-grade lesions

- Importance of High-Risk Human Papillomavirus Infection Detection in Female Renal Transplant Recipients in the First Year after Transplantation

- Esophageal squamous cell carcinomas in a Malaysian cohort show a lack of association with human papillomavirus

- High Burden of Human Papillomavirus Infection in Madagascar: Comparison With Other Sexually Transmitted Infections

- Prevalence of Vaccine Type Infections in Vaccinated and Non-Vaccinated Young Women: HPV-IMPACT, a Self-Sampling Study

- Prevalence of human papillomavirus genotypes and precancerous cervical lesions in a screening population in the Republic of Korea, 2014-2016

- Prevalence of Human Papillomavirus in Laryngeal Squamous Cell Carcinoma in Azerbaijan Population

- Type Distribution of Human Papillomavirus in Genital Warts of Korean Men

- Acceptability of Human Papillomavirus Self-Sampling for Cervical Cancer Screening in an Indigenous Community in Guatemala

- Comparison of the analytical and clinical performance of five tests for the detection of human papillomavirus genital infection

- HPV genotype-specific concordance between EuroArray HPV, Anyplex II HPV28 and Linear Array HPV Genotyping test in Australian cervical samples

- Prevalence of human papillomavirus and bacteria as sexually transmitted infections in symptomatic and asymptomatic women

- Options in human papillomavirus (HPV) detection for cervical cancer screening: comparison between full genotyping and a rapid qualitative HPV-DNA assay in Ghana

- Human Papillomavirus Genotype Distribution Among 18,815 Women in 13 Korean Cities and Relationship With Cervical Cytology Findings

- Chlamydia trachomatis and HPV co- infections in HIV negative men from a multi-ethnic area of Northern Italy at high prevalence of cervical malignancies

- No Detection of Episomal or Integrated High-Risk Human Papillomavirus in Nonsmall Cell Lung Carcinomas among Korean Population

- Comparison of initial stream urine samples and cervical samples for detection of human papillomavirus

- Comparison of Cobas® HPV and Anyplex™ II HPV28 assays for detecting and genotyping human papillomavirus

- Prevalence of human papillomavirus infection among women in rural Nepal

- Detection of Human Papillomavirus in Korean Breast Cancer Patients by Real-Time Polymerase Chain Reaction and Meta-Analysis of Human Papillomavirus and Breast Cancer

- Human Papillomavirus Prevalence and Type Distribution Among 968 Women in South Korea

- Comparison of initial stream urine samples and cervical samples for detection of human papillomavirus

- Anyplex II HPV28 detection and Anyplex II HPV HR detection assays are highly concordant with other commercial assays for detection of high-risk HPV genotypes in women with high grade cervical abnormalities.

- Multiple Human Papillomavirus Infection Is Associated with High-Risk Infection in Male Genital Warts in Ulsan, Korea

- Use of swabs for dry collection of selfsamples to detect human papillomavirus among Malagasy women

- Human papillomavirus prevalence and type-specific distribution of high- and low-risk genotypes among Malagasy women living in urban and rural areas

- HPV Genotyping from the high risk mRNA Aptima assay- a direct approach using DNA from Aptima sample tubes

- Performance evaluation of Anyplex™II HPV28 detection kit in a routine diagnostic setting: Comparison with the HPV Sign® Genotyping Test

- Type-specific persistence or regression of human papillomavirus genotypes in women with cervical intraepithelial neoplasia 1: A prospective cohort study

- Genotypic characterisation of human papillomavirus infections among persons living with HIV infection; a case–control study in Kumasi, Ghana

- Evaluation of HPV genotyping assays for archival clincal smaples

- Clincal validation of the Anyplex II HPV HR Detection for the Cervical Cancer Screening

- Comparison of the Anyplex II HPV28 assay with the Hybrid Capture 2 assay for the detection of HPV infection

- A case of HPV-53-related cervical cancer in an elderly patient

- Updating the PGMY primers and probes for improved detection of HPV68a: validation of version 2 of the PGMY-CHUV assay

- A very rare case of HPV-53-related cervical cancer, in a 79-year-old woman with a previous history of negative Pap cytology

- Human papillomavirus genotyping: comparison of the Seegene AnyplexTM II HPV28 with the PGMY-CHUV assay

- High prevalence of hpv multiple genotypes in women with persistent chlamydia trachomatis infection

- Prevalence of Human Papillomavirus Infection and Genotype Distribution Determined by the Cyclic-Catcher Melting Temperature Analysis in Korean medical checkup population

- Comparative Evaluation of the HPV28 Detection and HPV DNA Chip Test for Detecting and Genotyping Human Papillomaviruses